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Writer's pictureLayne Kilpatrick

The Perils of Bad Information


References are linked throughout the transcript below.


Transcript:

Sometimes data in studies gets so badly mismanaged and "statistically adjusted" that it starts to look suspiciously intentional. In 2013, a study was published in JAMA called Association of Testosterone Therapy With Mortality [death], Myocardial Infarction [heart attack], and Stroke in Men With Low Testosterone Levels. This poorly designed observational study found that all these events were significantly higher in men on testosterone therapy. This contradicted repeated findings over 30 years showing the opposite effect. The study was so bad that 20 medical societies and more than 150 medical scholars, researchers, and clinicians from 28 countries called for a retraction. And JAMA, with egg on their face, stood on their pride. They made a few minor corrections, but the damage was done. The press latched on to it and announced "We found out testosterone therapy is bad!" And so testosterone's image takes another hit. Is it deserved? Well, if it is, it wasn't proven by this disaster of a study. And I suspect their embarrassment will only get worse. The TRAVERSE trial, a 5 year, randomized, placebo-controlled, double blinded study on the same subject, looking at even more effects just concluded early in 2023. Their deadline to publish results is Jan, of '24. We're hopeful THAT study will be more meaningful.


Go to my bio and opt in on the All Things Testosterone Online Course to get notified about this course I'm putting together with all the resources for help. Coming up soon.


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